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SUPRAX is indicated in the treatment of adults and pediatric patients six months of age or older with pharyngitis and tonsillitis caused by susceptible isolates of Streptococcus pyogenesNotePenicillin is the usual drug of choice in the treatment of Streptococcus pyogenes infectionsSUPRAX is generally effective in the eradication of Streptococcus pyogenes from the nasopharynxhoweverdata establishing the efficacy of SUPRAX in the subsequent prevention of rheumatic fever is not available

Thereforethe tablet or capsule should not be substituted for the chewable tablets or suspension in the treatment of otitis mediasee Clinical Pharmacology12.3

Cdifficile produces toxins A and B which contribute to the development of CDADHypertoxin producing isolates of Cdifficile cause increased morbidity and mortalityas these infections can be refractory to antimicrobial therapy and may require colectomyCDAD must be considered in all patients who present with diarrhea following antibiotic useCareful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents.

Cefdinir and cefiximeSupraxare partially man madesemi-synthetic3rd generation antibiotics that belong to the drug class called cephalosporinsBacteria cannot survive without a cell wallso cephalosporins prevent the bacteria from multiplyingwhich then prevents bacteria from forming the walls that surround them.

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